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CLLPAG Conference

Bookmark this date and watch this space!

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Conference Update

Our CLL LIVE 2012 Conference preparations are progressing well and we have a great line up of well-known speakers including:

Dr Michael J Keating
MD Anderson Cancer Centre, Houston Texas
Dr Neil Kay
Mayo Clinic Rochester, Minnesota
Prof Dr Mathias Rummel
Klinikum der Justus-Liebig-Universität, Giessen, Germany
Dr Susan J. Leclair
Chancellor Professor University of Massachusetts Dartmouth
Andrew Schorr
Patient Power and Author of the Web Savvy Patient
Dr Ronan Foley ~ Conference Chair Juravinski Cancer Centre
Dr Graeme Fraser
Juravinski Cancer Centre ~ McMaster University
Dr Chaya Venkat
Co founder CLLTopics
Dr Stephen Couban
President of the Canadian Hematology Society
Dr Cynthia Toze
The Leukemia/Bone Marrow Transplant Program, B.C.
Dr Spencer Gibson
Director of Translational Research, MB Institute of Cell Biology

The CLL LIVE 2012 Conference website will be opened in mid-January 2012.

CLL News

Bendamustine batch recall in The US

Cephalon, Inc. issues a voluntary nationwide recall of Treanda® (bendamustine HCL) for Injection 25mg/Vial Due to Particulate Matter.

"Treanda (bendamustine HCL) for Injection 25mg/8mL is indicated for the treatment of chronic lymphocytic leukemia (CLL). Efficacy relative to first-line therapies other than chlorambucil has not been established. Treanda (bendamustine HCL) for Injection 25mg/8mL is indicated for the treatment of patients with indolent B-cell non-Hodgkin's lymphoma (NHL) that has progressed during or within 6 months of treatment with rituximab-containing regimen.

This recall is being conducted in consideration of the potential safety issue and risk associated with administration of this product lot. Potential adverse events after intravenous administration of solutions containing particulates may present as an emboli and result in disruption of blood flow causing tissue/organ damage, especially in vulnerable patients such as those undergoing surgery, immunosuppressed individuals, and the elderly, as well as patients with micro or macrovasular disease, such as cardiac and renal disease, who may be more at risk since their vasculature and end organs are already compromised. To date, Cephalon, Inc. has not received any adverse events associated with the use of this product lot that could be attributed to particulate matter. "
FDA LINK HERE
Jan 28, 2012

Dr. Gridden on CARs

Dr. John Gribben, a leading CLL Expert from the UK, explains CARs or chimeric antigen receptors like the ones that made news from Univ. of Penn last summer. He puts it all in perspective.

Patient Power video here: LINK HERE
Jan 27, 2012

CD to Support Leukemia Patients

bloodbrothers

All proceeds support leukemia patients at the QEII Health Sciences Centre.

Enjoy a musical journey of great R & B hits as well as some tried and true rock 'n roll. Listen to the hit single, You Don’t Understand,VIDEO HERE the story of Derek Caine's journey with CLL/SLL.

"One day it will win and I will lose but until that day I revel in the joy of life and in my family, friends and of course, music." - Derek Caine

ORDER TODAY: $20 CDN LINK HERE

Derek's Story on Video: CTV
Jan 25, 2012

Flavopiridol treatment of patients aged 70 or older

Dr. J. Byrd etc al, of OSU-James C.C., have studied flavopiridol in refractory and relapsed patients aged 70 years and older in a small clinical trial.

Flavopiridol, is a pan cyclin-dependent kinase inhibitor which has demonstrated noteworthy clinical activity in relapsed and refractory CLL patients including those with del(17p13.1) The common side effects observed with flavopiridol, including hyperacute tumour lysis syndrome (TLS), cytokine release syndrome (CRS), neutropenia, diarrhea and fatigue, are often seen but are manageable.

The study concluded, "Although our results are based on a relatively small cohort of patients aged 70 and older, there is currently no strong evidence that these older patients cannot tolerate or respond favourably to treatment with flavopiridol. Future development of treatment approaches with both single-agent flavopiridol and combination strategies of flavopiridol should be considered for older CLL patients. "

FULL PDF LINK HERE
Jan 23 , 2012
CCO_header

Highlights of ASH 2011 ~ CLL

Clinical Care Options has a review of ASH 2011 by John C. Byrd, MD, and Kanti Rai, MD, They highlight the most compelling data in the treatment of CLL presented at the 2011 American Society of Hematology Annual Meeting.

Summaries: LINK HERE
Slide set in PowerPoint: DOWNLOAD HERE
Jan 20 , 2012
Recent News 2012

Oct ~ Dec 2011

June ~ Oct 2011

January ~ June 2011
Did You Know?

Flow Cytometry ~ Everything you need to know and more...

Flow Cytometry is a blood test used to diagnose CLL. This video tutorial education program explains how flow cytometry actually works.

This takes about 12 minutes to view...

Flow Tutorial LINK HERE

Many other tutorials : LINK HERE

Also see the "How does FISH work?" LINK HERE
Nov 7, 2011
New CLL Website
Livingwcll Click Image Above

CLL TRACKER
Now Available

Link Here to CLL TRACKER
The CLL TRACKER has undergone a major revision...
CHECK IT OUT!
Understand Blood Labs
blood_labs
One of the most complete up-to-date website about blood tests can be found at this link. Well worth bookmarking for future reference.

Lab Tests Online

Guide to Lab Test for CLL

lab_test Click Here

Thanks to Beth for this link

Guide to Bloodwork ~ Complete Blood Count

This is an excellent resource you can save to disc and refer to.
Click Here for PDF

Blood count ranges can be found here:
Note that these ranges do vary from lab to lab and country to country.
Click Here
Only in Canada

Special Access Programme for Canadians

The Special Access Programme (SAP) allows practitioners to request access to drugs that are unavailable for sale in Canada. This access is limited to patients with serious or life-threatening conditions on a compassionate or emergency basis when conventional therapies have failed, are unsuitable, or are unavailable.

PDF INFO: LINK HERE

SAP Website

Did You Know?
"There are lots of anecdotal successes but the plural of anecdote is not evidence."
Dr.T. Hamblin

European CLL Guidelines

The European Society for Medical Oncology (ESMO) Guidelines Working Group have updated their clinical practice guidelines for CLL. These are the treatment guidelines often used throughout Europe
B. Eichhorst, M. Dreyling, T. Robak, E. Montserrat & M. Hallek
PDF Here: LINK HERE

Also see the 2008
CLL Treatment Guidelines: LINK HERE

NCI-WG 1996 treatment/diagnosis guide of CLL. This has been largely replaced by the 2008 Guidlines LINK HERE PDF

HOVON – the Haemato Oncology Foundation for Adults in the Netherlands Guidelines
LINK HERE PDF
Nov 6, 2011
Meetings & Events
The Leukemia and Lymphoma Society will be presenting highlights of the latest ASH (American Society of Hematology) Conference

Saturday, January 21, 2012 Marriott Hotel, Woodland Hills

9:00 - 10:30 Welcome, Introduction, and Keynote Speaker
10:30 - 12:00 Concurrent breakout sessions for each of the major blood
cancer diagnoses (Dr. Herbert Eradat will be the CLL speaker)
12:00 - 2:00 Lunch and Panel Discussion

Free, but Registration required For more information call 310 342 5838
or EMAIL HERE

The Leukemia Association of Ottawa

A support group based in Ottawa, Ontario dedicated to helping people with Leukemia and their care-givers, friends, and family.

Meetings are the 4th Tuesday of every month
7:00pm - 9:00pm
Riverside United Church,
3191 Riverside Drive (south of Walkley Rd)
Ottawa


Link to Website
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